Fine particulate matter (PM2.5) pollution is a primary global public health concern. Exposure to PM2.5 pollution beyond the safe limits of exposure is associated inter alia with respiratory and cardio-vascular mortality and morbidity. However, the baseline and background levels of PM2.5 concentration in megacities in India are significantly higher than the WHO Air Quality Guidelines which are based on studies conducted in regions with very low ambient PM concentrations. Human susceptibility to air pollution may vary based on age distribution, nutritional intake, access to health care, meteorological conditions, and any natural immunity. Therefore, it is essential to study the exposure-response function(s) specific to India using the local air pollution exposure studies.
On the other hand, the air quality monitoring stations used to measure ambient PM2.5 concentration are sparse and non-uniformly distributed in urban areas and nearly-absent in rural areas leading to the misclassification of exposure in India.
Therefore, the authors have developed a Linear Mixed Effects model in the present study to estimate PM2.5 levels in four major cities in peninsular India at a spatial resolution of 1 km x 1 km. Bengaluru (801 grids), Hyderabad (873 grids), Madurai (81 grids), and Vijayawada (88 grids) have been selected for this study since they are useful to estimate air pollution exposures for cities with different geographical, climatical, demographic and topographical conditions.